219 Patagonian native plant extract can protect cells from arsenic toxicity a6RWRPD\RU9a,bBongiovanni GA Chronic toxic effects of arsenic resulting from drinkLQJZDWHUDUHDKXPDQKHDOWKSUREOHPHVSHFLDOO\LQ 6RXWK$PHULFD DQG $VLD ZKHUH WKHUH LV D FRUUHODWLRQEHWZHHQR[LGDWLYHVWUHVVWXPRUSURPRWLRQDQG arsenic exposure.. In order to examine their protective potential, the antioxidant activity in different 3DWDJRQLDQ QDWLYH SODQW H[WUDFWV $UJHQWLQD ZHUH GHWHUPLQHG LQ YLWUR LQ WKH 9HUR FHOO OLQH PDPPDOLDQ NLGQH\ ([SHULPHQWDOO\ K\GURSHUR[LGH FDVSDVH DFWLYLW\DQG526OHYHOZHUHDVVD\HGWRHYDOXDWHWKH SURSHUWLHVRIHLJKWHHQH[WUDFWVFRPSDUHGE\$129$ IROORZHG E\ WKH /6' )LVKHU WHVW 'DWD VKRZHG WKDW DUVHQLWHZDVSURR[LGDQWLQ9HURFHOOVLQDWLPHDQG GRVHGHSHQGHQW PDQQHU ORJLVWLF UHJUHVVLRQ )LYH SODQW H[WUDFWV ZHUH IRXQG WR FRXQWHU WKH R[LGDWLYH stress response. Therefore, antioxidant substances DUHEHLQJSXULÀHGVLQFHWKH\PD\KDYHDSURWHFWLYH activity against arsenite-induced renal injury. a IDEPA (Instituto Multidisciplinario de Investigación y Desarrollo de la Patagonia Norte), CONICET-Universidad Nacional del Comahue. Neuquén, ARGENTINA (gabongiovanni@hotmail.com) b Facultad de Ciencias Agrarias, Universidad Nacional del Comahue. Río Negro, ARGENTINA. 9th International Symposium on Environmental Geochemistry