Maduración: definir y ejecutar planes para encarrilar el

JANUS DEVELOPMENTS DEVELOPING BIOMED INNOVATION
Maduración: definir y ejecutar planes para encarrilar el conocimiento en la cadena de valor
5 Septiembre 2011
Mª Isabel Berges
Managing Partner & CFO
mberges@janusdevelopments.com
01 MISSION AND UNMET NEED
Mission
To turn basic biomedical knowledge into social and economic value
04
02 METHODOLOGY AND PROJECT TYPES
“Encarrilar” en la cadena de valor
1. Establecer objetivos: hacia dónde vamos?
2. Conocer el entorno.
3. Visualizar el carril.
4. Ejecutar el proyecto en plazo.
08
02 METHODOLOGY AND PROJECT TYPES
“Encarrilar” en la cadena de valor
08
02 METHODOLOGY AND PROJECT TYPES
¿Por dónde salir del carril?
08
02 METHODOLOGY AND PROJECT TYPES
Standard project calendar
Acquisition of rights (in‐license or other agreements)
EXPLORATION 10
EXECUTION
Janus Development team.
Operational Project team
Work plan execution
Strategic project team
Janus Developments team
GAP, TPP, EXIT analysis (execution option)
EXIT
02 METHODOLOGY AND PROJECT TYPES
Methodology for analyzing and executing projects
1. In‐ licensing or agreement with technology originator
2. GAP analysis:
 Market interest, unmet needs and challenges
 IP protection or other barriers of entry
 Evidence and robustness that supports key selling attributes
 Feasibility of industrial production
 Possible exit strategies: license out, spin‐off, trade sale…
08
02 METHODOLOGY AND PROJECT TYPES
Methodology for analyzing and executing projects
3. Definition of work plan:
 Priorities
 Activities
 Budget
 Project team / specialized suppliers
4. Execution
5. License out – Build up of NewCo‐ Other exit strategy
09
03 THE TEAM
Virtual Project Teams
Specialist researchers
Proof of concept preclinical and clinical models
3P, Biotechnol, VGXI, Bioingenium Biologic products supply
Innoqua
Regulatory non‐clinical expert advice and project managment
Bioscience Valuation
Marketing research
JANUS TEAM
Strategic planning
Project Management
Business development (in‐out)
17
Enantia, other
Scale up chemistry processes, medicinal chemistry
ABG, Sterne, Kessler (NY), Hoffman Eitel (Ge), other: IP management
RPN
Regulatory affairs
Salutis, TFS
Clinical CROs
Technology originator
New molecules, proof of concept test…
Medical advisors adhoc, primary research
Idifarma, Phares
CMC and pharmaceutical development
02 METHODOLOGY AND PROJECT TYPES
Different types of projects
1. INTERNAL R&D PROJECT

IP licensed to JANUS with rights to develop and commercialize.

JANUS invests own financial resources for the development plan.

Business Model: License‐out to third party or build‐up in collaboration with VC. JANUS will receive milestone payments and royalties and distribute a percentage of revenue to technology originator, according to license agreement
2. MANAGEMENT CONSULTANCY PROJECT
11

Portfolio analysis, product development strategy and project management in the biomed area.

Project can be specific consultancy analysis with limited duration, or long term interim management agreement.

Business Model: JANUS receives services fee and success fee (cash or equity), according to agreed conditions.
05 ACHIEVED GOALS
Goals achieved from incorporation, in March 2009
CONSULTANCY
Consultancy projects executed
Interim Management executed
INTERNATAL R&D
Analyzed
Development initiated
% of acceptetance
Cancellled
Att. Rate JANUS
Out‐licensing agreements
27
46
5
58
17
29,31%
6
35,29%
2
05 ACHIEVED GOALS
Current investors and sources of capital
29
03
THE TEAM
Developing biomed innovations
03 THE TEAM
Founders
14
03 THE TEAM
Staff
15
03 THE TEAM
Non Executive Directors
16