IV INTERNATIONAL MEETING ON LIVING DONOR LIVER AND KIDNEY TRANSPLANTATION Barcelona – November 14 – 15 , 2005 PROGRAMME ORGANIZED BY: Hospital Clinic Liver Transplant Unit Renal Transplant Unit Transplant Coordination IV International Meeting on Living Donor Liver and Kidney Transplantation Barcelona (Spain) - November 14 - 15, 2005 WELCOME MESSAGE Dear friends and colleagues, Living donor kidney and liver transplantation continues to be a controversial issue to date.. Although the use of this type of organ transplantation is becoming more and more popular, this wide use involves, not only the development of the necessary surgical skills to do it, but also the need to develop awareness of the significance of this complicated process, inside or outside of the operating room, whether from the renal or the hepatic point of view. Thus the necessity to continuously evaluate the results achieved in the donor and the recipients side. The IV International meeting on living donor organ transplantation will be specifically focused in promoting living organ donation and transplantation as well as evaluating the current results of the literature. This will be done by the most outstanding leaders of the world. Specifically, the role of the transplant coordinators , as well as the different models of organ living donation worldwide will be analysed. Controversial issues, such as laparoscopic donor nephrectomy with regard to kidney, or recurrence of HCV after transplantation with regard to liver, will be studied. Perhaps the most interesting aspects of this new course is that we include the transmission of two live procedures; an adult kidney and liver transplantations. Those very long procedures will be inserted during the development of the program, so that the most interesting parts of both operations could be easily viewed by the audience, without having to stand for the whole operation. Although it is widely acknowledged that living donation has emerged as an efficient means to help in reaching the highest number of patients, the Hospital Clínic, pioneer in Spain in this type of procedures, maintains its commitment and responds to the need for continued evaluation and maximum transparency, allowing the Society and the Scientific community to verify the advances achieved during this period as well as evaluate the problems associated to the whole process. In this occasion, the Hospital Clínic together with the Catalan Transplant Organization (OCATT) and the National Transplant Organization (ONT), under the patronage of the Department of Health of the Government of Catalunya, would like to give you a warm welcome to Barcelona in the sureness that you will be getting, in this two days meeting, an overall view of living donation to date and its role in organ transplantation in the near future. Juan C.García-Valdecasas Liver Transplant Unit Federico Oppenheimer Renal Transplant Unit IV International Meeting on Living Donor Liver and Kidney Transplantation Barcelona (Spain) - November 14 - 15, 2005 HONOUR COMMITTEE: President Marina Geli Honorable Consellera de Sanidad Rafael Matesanz National Transplant Organization (ONT) Rosa Deulofeu Catalan Transplant Organization (OCATT) ORGANIZING COMMITTEE: HOSPITAL CLINIC: Transplant Coordination: Martí Manyalich Jordi Vilardell Liver Transplant Unit: Juan C. García-Valdecasas José Fuster Ramón Charco Constantino Fondevila Renal Transplant Unit: Federico Oppenheimer Antonio Alcaraz Jose María Campistol Rafael Gutiérrez Ricardo Álvarez With the collaboration of: Organización Nacional de Trasplantes (ONT) Organització Catalana de Trasplantaments(OCATT) Sociedad Española de Nefrología (SEN) Sociedad Española de Trasplante Hepático. Under the Patronage of the Health Adviser of the Generalitat of Catalunya. Faculty Antonio Alcaraz. Barcelona. Manuel Arias. Santander. Juan Ramón Ayuso. Barcelona. Olivie Boillot. Lyon. Ulla Berg. Stocolm. Fco. Javier Burgos. Madrid. Josep Maria Campistol. Barcelona. Ramón Charco. Barcelona. Valentín Cuervas Mons. Madrid. Rosa Deulofeu. Barcelona. Behzod Einollahi. Teherán. Sheung-Tat Fan. Hong Kong. Stuart M. Flechmer. Cleveland. Ingela Fehrman. Estocolmo. Constantino Fondevila. Barcelona. Xavier Forns. Barcelona. Jose Fuster. Barcelona. Juan Carlos García Valdecasas. Barcelona. José M. Grinyó. Barcelona. Manuel Gonzalez Molina. Málaga. Luis Guirado. Barcelona. Rafael Gutiérrez. Barcelona. Nigel Heaton. Londres. S.G. Lee. Corea del Sur. Jan Lerut. Belgium. Josep Lloveras. Barcelona. Massimo Malago. Essen. Amadeo Marcos. Pittsburgh. Carlos Margarit. Barcelona. Martí Manyalich. Barcelona. Faculty Rafael Matesanz. Madrid. José O. Medina. Sao Paulo. Gerardo Méndez Picón. Richmond. Jose Mª Morales. Madrid. Enrique Moreno González. Madrid. Robert Naraghi. Los Angeles. Miguel Navasa. Barcelona. Federico Oppenheimer. Barcelona. Fernando Pardo. Pamplona. Milagros Perea. Barcelona. Per Pfeffer. Oslo. Lloyd E. Ratner. Nueva York. Antoni Rimola. Barcelona. Antonio Rosales. Barcelona. Massimo Rossi. Roma. Albert Sánchez Fueyo. Barcelona. Kazunari Tanabe. Tokio. Pilar Taurá. Barcelona. Josep Terés. Barcelona. Guiliano Testa. Chicago. Gilbert Thiel. Basilea. Jordi Vilardell. Barcelona. Jonas Wadstrom. Uppsala. Willem Weimar. Rotterdam. Programa Científico / Scientific Program Curso Básico en la Coordinación: Análisis de diferentes modelos de donación en vivo. Basic Course of Coordination: Analysis of different world models of living donation. Retransmisión en directo desde un quirófano del Hospital Clínic: dos procedimientos de trasplante (trasplante renal y hepático.) Life transmission from the operating theatre of Hospital Clinic of two procedures (kidney and liver transplants). Tópicos en controversia en trasplante procedente de donante vivo. Topics to be discussed Riñón/Kidney: La laparoscopia en la nefrectomía en el donante. Donor laparoscopica neprectomy. Ventajas del trasplante renal de donante vivo. Resultados. Advantages of the living donor. Kidney transplant. Results. Hígado/Liver: Donante vivo y hepatocarcinoma. ¿La indicación ideal?. Living donor and hepatocellular carcinoma. Ideal indication?. Donante vivo y Virus de la Hepatitis C. ¿Una ventaja?. Living donor and virus C hepatitis. An advantage? “Small for size syndrome”. How to cope with it. CURSO BASICO / BASIC COURSE Coordinación en el Donante Vivo Transplant Coordination. Living Donors. 14 Noviembre 2005 / November 14th 2005 08:30 – 08:40 h. Presentanción del Curso. Introduction. M. Manyalich. (Barcelona). 08:40 – 09:00 h. Promoción y detección del donante vivo. Promoting and detecting living donors. J. Vilardell. (Barcelona). 09:00 – 09:15 h. Evaluación médica del Donante Renal. Medical evaluation of kidney donors. F. Oppenheimer. (Barcelona). 09:15 – 09:30 h. Evaluación quirúrgica del Donante Renal. Surgical evaluation of kidney donors. A. Alcaraz. (Barcelona). 09:30 – 09:45 h. Evaluación médica del Donante Hepático. Medical evaluation of liver donors. A. Sánchez Fueyo. (Barcelona). 09:45 – 10:00 h. Evaluación quirúrgica del Donante Hepático. Surgical evaluation of liver donors. C. Fondevila. (Barcelona). 10:00 – 10:10 h. Procedimientos de la Coordinación de Trasplantes. Procedures by transplant coordination. M. Perea.(Barcelona). 10:10 – 10:20 h. Procedimientos Comité de Ética. Procedures of the Ethic Committee. J. Terés (Barcelona). Presentación Caso Individual. A Case presentation. Evaluación Entorno Favorable. Environment favorable evaluation. CURSO BASICO / BASIC COURSE Coordinación en el Donante Vivo Transplant Coordination. Living Donors. 14 Noviembre 2005 / November 14th 2005 10:20 – 10:30 h. Procedimiento Registro Civil. Procedures of the Civil Judge. J. Vilardell (Barcelona) Consentimiento Informado Delante del Juez. Inform Consent. Firma de Testigos. Witnesses. 10:30 – 10:40 h. Discusión . / Discussion. 10:40 – 10:55 h. Café./Coffee Break. 10:55 – 11:15 h. Logistica del Donante Vivo. Living Donor Logistic. J.C. García-Valdecasas (Barcelona). Documento del New York Health Department. New York Department Consensus Document. 11:15 – 11:30 h. ASEDIVO – Testimonio. ASEDIVO – Testimony. 11:30 – 12:00 h. Conferencia de Prensa. Press Conference. 12:00 – 12:15 h. Inauguración del Curso. Official opening. Excma. Sra. Dª Marina Geli. Honorable Consellera de Sanidad Gobierno de Cataluña. Programa Científico / Scientific Program IV International Meeting on Living Donor Liver and Kidney Transplantation 14 Noviembre 2005 / November 14, 2005 12:15 – 13:35 h. SESION 1 / SESSION 1 Moderadores: Chairs: R. Deulofeu. (Barcelona). M. Manyalich. (Barcelona). 12:15 – 12:25 h. Evolución Donación de Vivo en España. Living donor evolution in Spain. R. Matesanz. (Madrid). 12:25 – 12:40 h. Un Modelo de Coordinación de Trasplante de Donante Vivo. The role of the transplant coordination in living donor. A. Model. J. Vilardell. (Barcelona). 12:40 – 12:55 h. Consenso International Forum Care of the Live Kidney Donor. International Consensus of the live kidney donor. F. Oppenheimer. (Barcelona). 12:55 – 13:15 h. Aspectos Económicos. Economic Aspects. G. Mendez-Picón.(Richmond.). 13:15 – 13:35 h. Aspectos Legales. Legal Aspects. Excmo. Sr. Adolfo Prego 13:35 – 15:00 h. Almuerzo de Trabajo. / Lunch. Programa Científico / Scientific Program IV International Meeting on Living Donor Liver and Kidney Transplantation 14 Noviembre 2005 / November 14, 2005 15:00 – 16:30 h. SESION 2/SESSION 2 Modelos Organizativos de la Donación de Vivo. World Organizing Models on living donors Moderadores: Chairs : J. Lloveras. (Barcelona). M. Navasa. (Barcelona.). 15:00 – 15:15 h. J. Medina. (Sao Paulo). 15:15 – 15:30 h. P. Pfeffer. (Oslo). 15:30 – 15:45 h. A. Marcos (Pittsburgh). 15:45 – 16:00 h. Sheung-Tat Fan (Hong Kong) 16:00 – 16:15 h. B. Einollahi (Teheran) 16:15 – 16:30 h. Discusión. / Discussion 16:30 – 17:15 h. Conferencia Magistral. State of The Art Lecture. Tolerancia y Donante Vivo. Tolerance and Living Donor. A. Marcos. (Pittsburgh). 17:15 – 17:30 h. Café./Coffee Break. 17:30 – 19:30 h. SESION 3/SESSION 3 INMUNOSUPRESION/IMMUNOSUPRESSION. Moderadores: Chairs: J.M. Grinyó. (Barcelona). V. Cuervas Mons. (Madrid). 17:30 – 17:50 h. Nuevas alternativas en la inmunosupresión del trasplante renal de donante vivo. New alternatives in immunosupression on living donor in kidney transplantation. L. Guirado (Barcelona) Programa Científico / Scientific Program IV International Meeting on Living Donor Liver and Kidney Transplantation 14 Noviembre 2005 / November 14, 2005 17:50 – 18:10 h. Monoterapia con Tacrolimus. Resultados de un estudio propectivo randomizado. Tacrolimus monotherapy. Results of a prospective randomized trial. J. Lerut.(Belgium) 18:10 – 18:30 h. Importancia MMF. Importance of MMF N.T.B.A. 18:30 – 18:50 h. Sirolimus como terapia base en el transplante de riñón en el donante vivo. Sirolimus as Base therapy in living donor kidney transplantation. S. Flechner. (Cleveland ). 18:50 – 19:10 h. Detección Tolerancia en Pacientes Imunodeprimidos. Tolerance detection in immunocompromied patients. A. Sánchez Fueyo.(Barcelona) Programa Científico / Scientific Program LIVING DONOR LIVER TRANSPLANTATION 15 Noviembre 2005 / November 15th, 2005 08:00 – 10:30 h. SESION 4/SESSION 4 DONANTE/DONORS Moderadores: Chairs: SALA “A”/ ROOM “A” F. Pardo. (Pamplona). M. Malago. (Essen). 08:00 – 08:30 h. Evaluación del donante. Donor Evaluation. A. Rimola. (Barcelona). 08:30 – 08:45 h. Conexión – Explicación del Caso. Connecting with the procedure. A case. R. Charco. (Barcelona). 08:45 – 09:15 h. La Resonancia Magnética. (Vascular, Biliar, Arterias). The value of the magnetic resonance. (Vascular, Biliary, Arterial). J.R. Ayuso. (Barcelona). 09:15 – 09:30 h. Conexión – Manejo Perioperatorio. Connecting with the procedure – Perioperative management. P. Taurá. (Barcelona). 09:30 – 10:00 h. La Vena Hepática Media. Evaluación Selectiva. The middle hepatic vein selective evaluation. S. Fan. (Hong Kong) 10:00 – 10:30 h. Conexión – Procedimiento. Connecting with the procedure. C. Fondevila. (Barcelona). 10:30 – 11:00 h. Café./Coffee Break. 11:00 – 11:45 h. Conferencia Magistral. State of the Art Lecture. Dos Donantes / Un Receptor – Menos Riesgo!! Two donors one recipient. Less risk!! S. G. Lee (Corea del Sur). Programa Científico / Scientific Program LIVING DONOR LIVER TRANSPLANTATION 15 Noviembre 2005 / November 15th, 2005 11:45 – 13:30 h. SESION 5/SESSION 5 Evitar Complicaciones Inmediatas. Avoiding immediate complications. Moderadores: Chairs: C. Margarit (Barcelona). N. Heaton. (Londres). Como lo hago. Drenaje Venoso. How I do it. Venous drainage. M. Malago. (Essen). Como lo hago. Anastomosis Arterial. How I do it. Arterial Anastomoses. G. Testa. (Chicago). Como lo hago. Anastomosis Biliar. How I do it. Biliary Anastomoses. A. Marcos. (Pittsburgh). Anastomosis Cond. A. Cond. Puntos de Controversia. Duct-to-duct anastomoses Controversial issues. S. Fan. (Hong Kong) 13:30 – 15:30 h. Almuerzo de Trabajo. Lunch. 15:30 – 17:00 h. SESION 6/ SESSION 6 RECEPTOR/ RECIPIENT 15:30 – 17:45 h. Conexión con procedimiento. Connecting with the procedure. Moderadores: Chairs: G. Testa. (Chicago). M. Rossi. (Roma). 15:30 – 15:50 h. HCC, DV e Indicación Expandida. Resultados Preliminares. HCC, DV and Expanded indication. Preliminary Results. J. Fuster (Barcelona). Programa Científico / Scientific Program LIVING DONOR LIVER TRANSPLANTATION 15 Noviembre 2005 / November 15th, 2005 15:50 – 16:05 h. Conexión con procedimiento. Connecting with the procedure. 16:05 – 16:25 h. VHC. El Donante Vivo como Ventaja? VHC.The living donor as an advantage? X. Forns. (Barcelona). 16:25 – 16:45h. Sindrome “Small for size”. ¿Como combatirlo?. “Small for size”. How to cope with it?. O. Boillot. (Lyon). 16:45 – 17:00 h. Conexión con procedimiento. Connecting with the procedure. 17:00 – 17:45 h. Conferencia Magistral State of the Art Lecture. Presentación /Introduction: J.C. García-Valdecasas (Barcelona). Trasplante Hepático de Donante Vivo. Estado Actual y Potencial futuro. Living Donor Living Transplantation. Current status and future trends. E. Moreno González. (Madrid). 17:45 – 18:00 h. Café./Coffee Break. 18:00 – 19:00 h. Mesa Redonda. Round Table. “Potenciar la donación en vivo en el mundo”. Moderadores: Chairs: F. Oppenheimer (Barcelona). J.C. García-Valdecasas (Barcelona). Ponentes: Speakers: J. Medina (Sao Paulo) G. Mendez-Picón (Richmond) A. Marcos (Pittsburgh) R. Deulofeu (Barcelona) A. Alcaraz (Barcelona Programa Científico / Scientific Program LIVING DONOR KIDNEY TRANSPLANTATION 15 Noviembre 2005 / November 15th 2005 08:00 – 10:30 h . SALA “B” / ROOM “B” Moderadores: Chairs: A. Rosales (Barcelona). M. González-Molina (Málaga) 08:00 – 08:20 h. Valoración nefrológica del donante. Kidney donor evaluation. G. Thiel (Basilea). 08:20 – 08:30 h. Discusion. / Discussion. 08:30 – 09:00 h. Conexión – Explicación del Caso. Connecting with the procedure – A case. R. Gutiérrez. (Barcelona). 09:00 – 09:30 h. Análisis Clínico de diferentes alternativas técnicas. Surgical approach. Analysis of different procedures. Ll. Ratner.(Filadelfia). 09:30 – 10:00 h. Nefrectomía mano-asistida con abordaje retroperitoneoscópico. Hand-assisted retroperitoneoscopic live donor nephrectomy. J. Wadstrom. (Uppsala) 10:00 – 10:30 h. Conexión – Procedimiento. Connecting with the procedure. 10:30 – 11:00 h. Café. / Coffee Break. 11:00 – 13:30 h. SESION 1 / SESSION 1 Moderadores: Chairs: F.J. Burgos (Madrid) L. Guirado (Barcelona) 11:00 – 11:20 h. Resultado de la minilumbotomía. Minilumbotomy Results. R. Naraghi. (Los Angeles). 11:20 – 11:30 h. Discusión. / Discussion. Programa Científico / Scientific Program LIVING DONOR KIDNEY TRANSPLANTATION 15 Noviembre 2005 / November 15th 2005 11:30 – 11:50 h. Impacto de la edad del donante. Donor age impact. K. Tanabe. (Tokio). 11:50 – 12:00 h. Discusión. / Discussion. 12:00 – 12:20 h. Estudio de la reserva funcional en el donante. Evaluation of the functional reserve in the donor. J.M. Campistol. (Barcelona) 12:20 – 12:30 h. Discusión. / Discussion. 12:30 – 12:50 h. Impacto de la técnica en la función renal. Impact of the surgical technique in the donor renal function. A. Alcaraz (Barcelona). 12:50 – 13:00 h. Discusión. / Discussion. 13:00 – 13:20 h. Impacto a largo plazo de la nefrectomía en el donante vivo. Long Term effect of living donor nephrectomy. I.Fehrman (Estocolmo) 13:20 – 13:30 h. Discusión. / Discussion. 13:30 – 15:30 h. Almuerzo de Trabajo. / Lunch. 15:30 – 18:00 h. SESION 2 / SESSION 2 Moderadores: Chairs: M. Arias (Santander) J.Mª Morales (Madrid) 15:30 – 15:50 h. Tx. Renal ABO incompatible (I). ABO incompatible kidney Tx (I). K. Tanabe. (Tokio). 15:50 – 16:10 h. Intercambio de donantes para trasplante renal. Donor exchange for renal transplantation. W. Weimar (Rotterdam). Programa Científico / Scientific Program LIVING DONOR KIDNEY TRANSPLANTATION 15 Noviembre 2005 / November 15th 2005 16:10 – 16:20 h. Discusión. / Discussion. 16:20 – 16:40 h. Resultados en el adulto (I). Adult Results (I). F. Oppenheimer. (Barcelona). 16:40 – 17:00 h. Resultados en el aulto (II). Adult Results (II). L. Guirado (Barcelona.). 17:00 – 17:20 h. Resultados Infantil. Pediatric Results. U. Berg (Estocolmo) 17:20 – 17:30 h. Discusión. / Discussion. 17:30 – 18:00 h. Café / Coffee Break. 18:00 – 19:00 h. Mesa Redonda. Round Table. “Potenciar la donación en vivo en el mundo”. . Moderadores: Chairs: F. Oppenheimer (Barcelona). J.C. García-Valdecasas (Barcelona). Ponentes: Speakers: J. Medina (Sao Paulo) G. Mendez-Picón (Richmond) A. Marcos (Pittsburgh) R. Deulofeu (Barcelona) A. Alcaraz (Barcelona) INFORMACION GENERAL GENERAL INFORMATION Meeting Venue: Hotel Fira Palace Avda. Rius i Taulet, 1-3 – 08004 Barcelona (Spain) Tel.: + 34 93 42 62 223 – Fax: + 34 93 42 48 679 Organizing Secretariat: OASIS Viajes y Congresos Director: Luis Micieces C/ Sor Angela de la Cruz, 8 28020 Madrid – Spain - Tel: +34 91 555 11 19 - Fax: +34 91 555 35 81 E-mail: livingdonor@viajesoasis.com - Web: www.viajesoasis.com Registration: All attendees must be registered to attend the IV International Meeting on Living Donor and Kidney Transplantation. Confirmation: Once the registration form has been received together with the relevant payment, the Secretariat will acknowledge receipt and will send the confirmation of the registration. Policy of Cancellation of Registration: Cancellations must be made in writing to the Secretariat. The refunds will be made after the meeting. All cancellations made before September 20th have a refund of 75% of the amount paid. No refund after mentioned date. Badges: The organization kindly requests people attending this meeting to wear their badges in order to access to the scientific sessions and other events scheduled. Exhibition: Be sure to visit the exhibition during the meeting, informative and important components of this event provide you with a valuable opportunity to meet representatives from various International Companies that are committed to the field of the Hepatology and Nephrology Living Donor Transplantation. Slide Preview Room: This hall will be provided for speakers and presenters to prepare their presentations. All speakers should check into this room with a minimum of one hour prior to starting the sessions. The meeting rooms will be equipped with the standard audiovisual, (Power Point presentation in all sessions). Meeting Language: English is the language of the Meeting. So all presentations and slides must be prepared in English. Cameras and Cell Phones: No Cameras or videocameras are allowed in any event during the meeting. As a courtesy to fellow attendees kindly turn off cells phones. Certificate of attendance: This will be available for participants who request it at the Secretariat desk in the venue. IV International Meeting on Living Donor Liver and Kidney Transplantation Barcelona (Spain) - November 14 - 15, 2005 REGISTRATION AND ACCOMMODATION FORM Surname ____________________ Name___________________________________ Address _____________________________________________________________ City ___________________ Country ________________ Postal Code___________ Telephone______________ Fax ______________ E-mail _____________________ Working Institution ____________________________________________________ Registration fee Before August 15, 2005 After August 16, 2005 Members ELTA 375 € 400 € Members ENA No Members Both ELTA / ENA Trainees 375 € 400 € 400 € 425 € 210 € 225 € FEE PAID Hotel Accommodation: Hotel Double room two persons Single room 195 € 168 € Fira Palace Price are per day per room including buffet breakfast and VAT. Arrival date__________ Departure date_________ Total nights: HOTEL BOOKING TOTAL AMOUNT Form of payment: Bank draft payable to VIAJES OASIS or credit card VISA – MASTER CARD and AMERICAN EXPRESS to be returned together with the registration form to the Organizing Secretariat: C/ Sor Angela de la Cruz, 8 28020 Madrid (Spain) VISA MASTER CARD AMERICAN EXPRESS Credit Card Number Expiry date Date ______________________ Authorized signature: