Curso Seg. Alimentaria - Fisabio

International Course on “Analysis of residues and contaminants in food samples using
chromatographic methodologies coupled to mass spectrometry in an official accredited
laboratory according to the ISO 17025”
Course description:
This International Course on Analysis of residues and contaminants in food samples is
focused on the analysis of some of the main residues and contaminants in different
matrices, according to the official control programmes of the European Union. The course
is delivered through a stimulating mix of seminars and practical work using state-of-theart analytical equipment. This training course offer several theoretical and practical
sessions about sample preparation, instrumental analysis, data evaluation and reporting,
under quality criteria and managed by a laboratory information system (LIMS).
FUNDACIÓN PARA EL FOMENTO DE LA INVESTIGACIÓN SANITARIA Y BIOMÉDICA DE LA COMUNITAT VALENCIANA.
Avda. Cataluña, 21. 46020 Valencia. CIF.: G98073760 Inscrita Rgtro.fundaciones: 501 V - www.fisabio.es
For more information, please contact to:
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Director: Dr Vicent Yusà (yusa_vic@gva.es)
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Coordinators: Dr Clara Coscollà (coscolla_cla@gva.es) / Dr Marta Roca
(roca_marmar@gva.es) . (Phone: 00 (+34) 96 192 59 00)
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Administrator: Beatriz Chacartegui (e-mail: chacartegui_bea@gva.es, phone: 00 (+34)
96 192 59 09)
Objectives:
• Provide theoretical knowledge on the analysis of residues and contaminants in food safety
using cutting-edge confirmatory analytical methodologies.
• Acquire practical skills on the methodologies of analysis of veterinary drugs and organic
pollutants with LC-MS/MS, GC-MS/MS and LC-HRMS.
• Work in an environment with a quality assurance system accreditated according to ISO
17025 and using a powerful laboratory information management system (LIMS).
Venue:
This course is delivered using facilities at LSPV-FISABIO, located on Avenida
Catalunya, 21, Valencia, Spain.
The Public Health Laboratory of Valencia (LSPV) is part of the Health Department of
the Regional Government of Valencia (Generalitat Valenciana). The mission of the
LSPV is to provide a reliable analytical system in support to the programmes of food
safety and environmental control promoted by the Valencia Regional Government
(Generalitat Valenciana). The laboratory employs more than 80 staff, 35 of whom with
Ph.D., M.S. or B.S. degrees. LSPV works under the quality system ISO/IEC 17025 and
is accreditated by the National Accreditation Entity ENAC. LSPV Laboratory is among
the biggest and best-equipped laboratories in Spain with modern facilities and equipped
with the latest and most modern analytical instruments. It is divided into four units, i.e.
Microbiological Department, Chemical Analysis Unit, Organic Contaminants and
Veterinary Residues.
FUNDACIÓN PARA EL FOMENTO DE LA INVESTIGACIÓN SANITARIA Y BIOMÉDICA DE LA COMUNITAT VALENCIANA.
Avda. Cataluña, 21. 46020 Valencia. CIF.: G98073760 Inscrita Rgtro.fundaciones: 501 V - www.fisabio.es
Course dates:
Dates are flexible and adapted to demand.
Timetable (flexible): 9.00 a.m.-17.00 p.m.
Attendants:
Professionals seeking to update or expand their knowledge of specific analytical areas
within an EU regulatory framework. They will improve their technical skills and
knowledge, and develop best practice techniques for their own labs, as they progress
towards accreditation. Course sizes are kept to a minimum to ensure each student
(maximum two students per group) has access to instruments, as well as time to address
his specific topics of interest.
Course lecturers:
The training course will be taught by different PhD scientists and technicians with
recognised experience in these analytical fields and with a scientific production in
different research areas.
Instructors:
MºIsabel Beser. FISABIO Researcher, Organic Pollutants Department. Public Health Laboratory of
Valencia (beser_mar@gva.es).
Clara Coscollà, PhD. FISABIO Researcher, Organic Pollutants Department. Public Health Laboratory
of Valencia (coscolla_cla@gva.es).
Carmen Igualada, FISABIO Researcher. Veterinary Drug Residues Department, Public Health
Laboratory of Valencia (igualada_car@gva.es).
Nuria León, FISABIO Researcher. Veterinary Drug Residues Department, Public Health Laboratory of
Valencia (leon_nur@gva.es).
Francisco Moragues, PhD. FISABIO Researcher. Veterinary Drug Residues Department, Public
Health Laboratory of Valencia (moragues_fra@gva.es).
Marta Roca, PhD. FISABIO Researcher, Organic Pollutants Department. Public Health Laboratory of
Valencia (roca_marmar@gva.es).
FUNDACIÓN PARA EL FOMENTO DE LA INVESTIGACIÓN SANITARIA Y BIOMÉDICA DE LA COMUNITAT VALENCIANA.
Avda. Cataluña, 21. 46020 Valencia. CIF.: G98073760 Inscrita Rgtro.fundaciones: 501 V - www.fisabio.es
Vicent Yusà, PhD. Head of the Food Safety Research Area (FISABIO). Associate Professor,
Department of Analytical Chemistry, University of Valencia (e-mail: yusa_vic@gva.es. Research Gate
profile: www.researchgate.net/profile/Vicent_Yusa/)
Language:
English/Spanish
Fees (taxes included):
7.000 euros/course for one student and 10.000 euros/course for two students.
STANDARD PROGRAMME (8 days: 57 hours)
The programme is flexible and will be adapted to demand.
Day 1 (theory sessions) (7 hours)
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Session 1: Quality system in an official control laboratory: official samples,
registration and traceability, quality management, validation and accreditation
(ISO 17025) and use of LIMS (Laboratory information management system)
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Session 2: Sample preparation for residues and contaminants analysis
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Session 3: Validation methods for the analysis of residues and contaminants
according to European regulations
Day 2 (theory sessions) (7 hours)
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Session 1: Analytical techniques: LC-MS/MS and GC-MS/MS
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Session 2: Analytical techniques: HRMS
Day 3 (practical session) (8 hours)
Application 1: Application on veterinary drugs adapted to demand
(Example Analysis of quinolones in animal tissues by LC-MS/MS)
Morning:
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Legal context and importance of the analysis
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Sample registration
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Sample preparation using SPE extraction
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Standards and quality controls
FUNDACIÓN PARA EL FOMENTO DE LA INVESTIGACIÓN SANITARIA Y BIOMÉDICA DE LA COMUNITAT VALENCIANA.
Avda. Cataluña, 21. 46020 Valencia. CIF.: G98073760 Inscrita Rgtro.fundaciones: 501 V - www.fisabio.es
Afternoon:
Use of LC-MS/MS:
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Verification and maintenance of the equipment
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Tuning and stabilization of the chromatographic system
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Description and setting of the Instrument Method
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Setting and injection of the working sequence
Day 4 (practical session) (8 hours)
Application 2: Application on organic pollutants adapted to demand.
(Example Analysis of Polybrominated Diphenyl Ethers (PBDEs) in Fish by GC-MS/MS)
Morning:
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Legal context and importance of the analysis
-
Sample registration
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Sample preparation using Liquid-liquid extraction
- Standards and quality controls
Afternoon:
Use of GC-MS/MS:
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Verification and maintenance of the equipment
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Description and setting of the Instrument Method
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Setting and injection of the working sequence
Day 5 (practical session) (7 hours)
Morning:
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Data processing for application 1 (LC-MS/MS)
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Set up of the Processing Method
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Quantification and confirmation of analytes using Trace Finder software
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Data interpretation and results
Afternoon:
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Data processing for application 2 (GC-MS/MS)
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Set up of the Processing Method
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Quantification and confirmation of analytes using Trace Finder software
-
Data interpretation and results
FUNDACIÓN PARA EL FOMENTO DE LA INVESTIGACIÓN SANITARIA Y BIOMÉDICA DE LA COMUNITAT VALENCIANA.
Avda. Cataluña, 21. 46020 Valencia. CIF.: G98073760 Inscrita Rgtro.fundaciones: 501 V - www.fisabio.es
Day 6 (practical session) (8 hours)
Application 3: Application using LC-HRMS adapted to demand.
(Example Analysis of banned veterinary drugs in feed by HRMS)
Morning:
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Legal context and importance of the analysis
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Generic sample preparation
- Standards and quality controls
Afternoon:
Use of Exactive:
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Verification and maintenance of the equipment
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Calibration and stabilization of the chromatographic system
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Description and setting of the Instrument Method
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Setting and injection of the working sequence
Day7 (practical session) (7 hours)
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Processing method and data processing for application 3
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Quantification and confirmation of analytes using Exact Finder software
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Data interpretation and results
Day 8 (practical session) (5 hours)
Morning:
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Submit results of applications to LIMS system
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Course evaluation and questions
How to register:
To register for this course please visit our website at www.fisabio.san.gva.es.
formacion_fisabio@gva.es
You will also find on our website useful information about the venue and the details of how to
find us.
Official accreditation of this course is currently in process.
FUNDACIÓN PARA EL FOMENTO DE LA INVESTIGACIÓN SANITARIA Y BIOMÉDICA DE LA COMUNITAT VALENCIANA.
Avda. Cataluña, 21. 46020 Valencia. CIF.: G98073760 Inscrita Rgtro.fundaciones: 501 V - www.fisabio.es