Facultad de Medicina Departamento de Fisiología FISIOLOGÍA HUMANA BLOQUE 7. SISTEMA RENAL y EQUILIBRIO HIDROELECTROLÍTICO Tema 30. Mecanismos de Concentración de la Orina Dr. Bernardo LÓPEZ‐CANO Profesor Titular de la Universidad de Murcia Contenidos Homeostasis hidroelectrolítica Concentración de la Orina • Vasopresina u Hormona Antidiurética (ADH) • Sistema de Intercambio por Contracorriente Asa de Henle Vasos Rectos Papel de la urea en la concentracion de la orina Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings Compartimentos Líquidos del Organismo Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings Deshidratación Extra e Intracelular 1 Excessive loss of H2O from ECF 2 ECF osmotic pressure rises (a) Mechanism of dehydration Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings 3 Cells lose H2O to ECF by osmosis; cells shrink Hidratación Extra e Intracelular 1 Excessive H2O enters the ECF 2 ECF osmotic pressure falls (b) Mechanism of hypotonic hydration Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings 3 H2O moves into cells by osmosis; cells swell Homeostasis Hidroelectrolítica Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings Balance de Agua Corporal Copyright © 2007 Pearson Education, Inc., publishing as Cummings Benjamin Cummings Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Balance de Agua Corporal Copyright © 2007 Pearson Education, Inc., publishing as Cummings Benjamin Cummings Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Osmolaridad de la Orina Copyright © © 2007 Inc., publishing Copyright 2007 Pearson Pearson Education, Education, Inc., publishing as as Benjamin Benjamin Cummings Cummings Neurohipófisis: Vasopresina o ADH Copyright Pearson Education, Inc.,Inc. publishing as Benjamin Copyright © ©2007 The McGraw-Hill Companies, Permission required Cummings for reproduction or display Formación de Orina Concentrada o Diluida: Vasopresina o ADH Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings Mecanismo de Acción de la Vasopresina Copyright © © 2007 Inc., publishing Copyright 2007 Pearson Pearson Education, Education, Inc., publishing as as Benjamin Benjamin Cummings Cummings Neurohipófisis: Vasopresina o ADH Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings Factores que Afectan a la Liberación de Vasopresina o ADH Copyright © © 2007 Inc., publishing Copyright 2007 Pearson Pearson Education, Education, Inc., publishing as as Benjamin Benjamin Cummings Cummings Efecto de la Osmolaridad Plasmática sobre la Secreción de Vasopresina o ADH Copyright © 2007Education, Pearson Education, Inc., publishing as Cummings Benjamin Cummings Copyright © 2007 Pearson Inc., publishing as Benjamin Efecto de la Osmolaridad Plasmática sobre la Secreción de Vasopresina o ADH Copyright © © 2007 Inc., publishing Copyright 2007 Pearson Pearson Education, Education, Inc., publishing as as Benjamin Benjamin Cummings Cummings Reabsorción Distal de Sodio: Aldosterona Copyright © © 2007 Inc., publishing Copyright 2007 Pearson Pearson Education, Education, Inc., publishing as as Benjamin Benjamin Cummings Cummings Reabsorción Distal de Sodio: Aldosterona Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings Mecanismo de Acción de la Aldosterona Copyright © © 2007 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Sistema Multiplicador de Contracorriente en el Asa de Henle Copyright Pearson Education, Inc.,Inc. publishing as Benjamin Copyright © ©2007 The McGraw-Hill Companies, Permission required Cummings for reproduction or display Intercambio de Contracorriente en los Vasos Rectos Copyright Pearson Education, Inc.,Inc. publishing as Benjamin Copyright © ©2007 The McGraw-Hill Companies, Permission required Cummings for reproduction or display Intercambio de Contracorriente en el Asa de Henle y Vasa Recta Copyright©©2007 2007Pearson PearsonEducation, Education,Inc., Inc.,publishing publishingas asBenjamin BenjaminCummings Cummings Copyright Intercambio de Contracorriente en el Asa de Henle y Vasos Rectos Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings Formación de Orina Diluida y Concentrada: Papel de la Urea Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings Formación de Orina Diluida y Concentrada: Papel de la Urea Copyright Pearson Education, Inc.,Inc. publishing as Benjamin Copyright © ©2007 The McGraw-Hill Companies, Permission required Cummings for reproduction or display Formación de Orina Concentrada o Diluida: Resumen http://www.physiol.med.uu.nl/interactivephysiology/ipweb/home/index2.html ADH Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings Formación de Orina Concentrada o Diluida: Resumen http://www.physiol.med.uu.nl/interactivephysiology/ipweb/home/index2.html Mecanismo de Contracorriente Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings