SciFinder® Essential Content. Proven Results.™

SciFinder®
Essential Content. Proven Results.™
Míriam Plana (mplana@cas.org)
This image cannot currently be
display ed.
2
CAS Databases
“Being able to rapidly search for important chemical information while
an idea is fresh in your mind is almost priceless. CAS databases
streamline the investigative process – allowing you to take an idea
and rapidly find the important and necessary information before you
forget about the idea or it loses its excitement. That really is
invaluable.”
Dr. Robert H. Grubbs
Nobel Laureate
Victor and Elizabeth Atkins Professor of Chemistry
California Institute of Technology
CAS is a division of the American Chemical Society.
Copyright 2013 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
CAS provides information to support scientists’ and
patent searchers’ workflows
CAS
REGISTRY
3
This image cannot currently be
display ed.
4
CAS REGISTRYSM is the gold standard for chemical
substance information
CAS is a division of the American Chemical Society.
Copyright 2013 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
5
CAS REGISTRY is the only integrated, complete
source of chemical information
CAS is a division of the American Chemical Society.
Copyright 2013 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
6
CAplusSM is your single source for chemistry and
related scientific information
CAS is a division of the American Chemical Society.
Copyright 2013 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
7
CAplus coverage of patents from Asia is unmatched
)
Japanese Patent Office (JP
China (CN)
India (IN)
Republic of Korea (KR
)
Taiwan (TW)
Hong Kong (HK)
Philippines (PH)
Malaysia (MY)
Singapore (SG)
CAS is a division of the American Chemical Society.
Copyright 2013 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
8
CASREACT® is the authoritative source for chemical
reactions
CAS is a division of the American Chemical Society.
Copyright 2013 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
9
CASREACT answers your chemical reaction
questions quickly, precisely, comprehensively
CAS is a division of the American Chemical Society.
Copyright 2013 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
CHEMCATS® is the definitive collection of
commercially available chemicals and suppliers
CAS is a division of the American Chemical Society.
Copyright 2013 American Chemical Society. All rights reserved.
10
This image cannot currently be
display ed.
11
CHEMCATS provides fast access to chemical
suppliers
CAS is a division of the American Chemical Society.
Copyright 2013 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
12
CHEMLIST® is the comprehensive source for
information on regulated chemicals
CAS is a division of the American Chemical Society.
Copyright 2013 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
13
CHEMLIST enables you to discover how and where
substances are regulated
CAS is a division of the American Chemical Society.
Copyright 2013 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
14
MARPAT® is the leading collection of Markush
structures from the world’s patent literature
CAS is a division of the American Chemical Society.
Copyright 2013 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
15
MARPAT supports maximum recall of patented
information
CAS is a division of the American Chemical Society.
Copyright 2013 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
16
CAS products streamline access to CAS databases
to speed the pace of scientific discovery
CAS is a division of the American Chemical Society.
Copyright 2013 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
17
SciFinder
“I am a big user and don’t see how any researcher could hope to
excel without daily, round-the-clock access. The speed and scope of
its search power is amazing… In my case, SciFinder enhances my
reactivity insights, making it easier to “see” those ill-defined
boundaries where important new phenomena are lurking.”
Dr. K. Barry Sharpless
Nobel Laureate
W.M. Keck Professor of Chemistry
Scripps Research Institute
CAS is a division of the American Chemical Society.
Copyright 2013 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
18
What’s new on SciFinder
CAS is a division of the American Chemical Society.
Copyright 2013 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
What’s new on SciFinder
1.- New Non-Java CAS Structure Editor
This image cannot currently be
display ed.
What’s new on SciFinder
2.- Analyze by reagents
This image cannot currently be
display ed.
What’s new on SciFinder
3.- Substance Quick View in Commercial Sources Answer Sets
by reagents
This image cannot currently be
display ed.
What’s new on SciFinder
4.- Commercial Supplier Email Hyperlinks
This image cannot currently be
display ed.
What’s new on SciFinder
5.- Increased Availability of SciPlanner Tutorials
This image cannot currently be
display ed.
24
What’s new on SciFinder
6.- Enhanced Account Management
This image cannot currently be
display ed.
25
What’s new on SciFinder
7.- Content Addition
This image cannot currently be
display ed.
26
What’s new on SciFinder
8.- New SciFinder Design
This image cannot currently be
display ed.
“I need to change something on my account.”
Ask us! We can help. • Account information • How to
• IT support
“Can I speak with someone in IT?”
Phone: 1‐800‐753‐4227 (North America)
1‐614‐447‐3700 (outside North America)
Email: help@cas.org
“I need help with my search strategy.”
Web: www.cas.org
This image cannot currently be
display ed.
28
Comprehensive Content
Sophisticated Analysis
Unprecedented Results
Thank You
Dra. Míriam Plana
CAS Regional Marketing Manager Spain & Portugal
mplana@cas.org
CAS is a division of the American Chemical Society.
Copyright 2013 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
Live demo
SciFinder options
Searches: topic, structure, reaction
Analysis tools
29
This image cannot currently be
display ed.
EJERCICIO (QI, QO, QA, Q General)
Buscar polímeros con esta estructura:
1.- No se permite fusión con otros anillos ni sustituciones adicionales al
alquilo ni al carbono.
2.- Encontrar literatura que hable de aplicaciones magnéticas en
nanotecnología de dichos polímeros en el campo de la medicina.
¿Para qué se utilizan?
3.- ¿Quién trabaja sobre este tema?
4.- Encontrar algún artículo que hable específicamente de cápsulas de
nanopartículas magnéticas.
5.- ¿Cómo podríamos preparar algún polímero? Busca una posible vía de
síntesis del polímero con el monómero cuyo CAS RN es 7085-85-0, que esté
formada por más de 2 reacciones y que el procedimiento experimental
This image cannot currently be
display ed.
EJERCICIO (QO)
Preparar esta sustancia:
1.- Mínimo número de etapas, en las distintas reacciones.
2.- Buen rendimiento
3.- Procedimientos experimentales
4.- ¿Para qué sirven este tipo de sustancias?
5.- ¿Quién trabaja con este tipo de sustancias?
CAS is a division of the American Chemical Society.
31
Copyright 2011 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
EJERCICIO (QA)
Buscar estudios sobre cómo medir potenciales Redox con voltametría
cíclica de complejos de renio, rutenio o platino con la 4,7-Fenantrolina:
Buscar también el punto de fusión de alguna sustancia con platino.
CAS is a division of the American Chemical Society.
32
Copyright 2011 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
EJERCICIO (Q General)
Interacción de medicamentos con el zumo de pomelo, concretamente de la
Atorvastatina y del Sildenafilo:
Atorvastatin
Sildenafil
CAS is a division of the American Chemical Society.
33
Copyright 2011 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
EJERCICIO (QI)
Buscar óxidos o nitruros que contengan Aluminio con Titanio o cromo.
1.- ¿Para qué se utilizan mayoritariamente este tipo de compuestos?
2.- ¿Quién está trabajando con estos compuestos en España?
3.- Encontrar algún artículo que hable de composites cerámicos de Al2O3Al2TiO5
CAS is a division of the American Chemical Society.
34
Copyright 2011 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
EJERCICIO (Q General (Biología, etc.)).
Buscar vacunas contra tumores renales.
1.- Que se utilicen en radioterapia.
2.- ¿Hay estudios con compuestos tipo Lactoferrina?
3.- ¿Quién trabaja sobre este tema? ¿Hay alguna patente?
CAS is a division of the American Chemical Society.
35
Copyright 2011 American Chemical Society. All rights reserved.
Míriam Plana
CAS Regional Marketing Manager, Spain & Portugal
mplana@cas.org
This image cannot currently be
display ed.
Example 1: Search for polymers with this structure
37
This image cannot currently be
display ed.
Substructure search limited to polymers only
38
This image cannot currently be
display ed.
677 polymer structures sorted to most cited compound
39
This image cannot currently be
display ed.
Refine 2376 references to Nanotechnology including
other nano-synonyms
40
This image cannot currently be
display ed.
Refine 1158 reference to magnetic applications
41
This image cannot currently be
display ed.
54 references with University of Granada at the top
42
This image cannot currently be
display ed.
Pubmed (Medline) has only 5 references out of 54
43
This image cannot currently be
display ed.
Great advantage of CAS indexing of topics and compounds
44
This image cannot currently be
display ed.
SciFinder has advanced options for analysis by Medicine
application
45
This image cannot currently be
display ed.
..or by type of polymers indexed
46
This image cannot currently be
display ed.
Míriam Plana
CAS Regional Marketing Manager, Spain & Portugal
mplana@cas.org
This image cannot currently be
display ed.
Example 2: Check novelty and design your synthesis
Research topic:
Looking for novelty on benzo-fused
heterocyclic sulfamides, their
possible pharmacological activity
and synthesis pathway
CAS is a division of the American Chemical Society.
48
Copyright 2011 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
October 25, 2013
Search substances with chemical structures or other
substance information to check novelty of substances
CAS is a division of the American Chemical Society.
49
Copyright 2011 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
SciFinder produces 99 compounds from the journal and
patent literature as well as from catalogs and libraries
CAS is a division of the American Chemical Society.
50
Copyright 2011 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
SciFinder retrieves 31 journal and patent references that
disclose one or more of the 99 compounds
CAS is a division of the American Chemical Society.
51
Copyright 2011 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
Categorize is a powerful tool to analyze the concepts and
substances indexed in the retrieved answer set
CAS is a division of the American Chemical Society.
52
Copyright 2011 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
A Markush search can produce additional patents
matching the broad generic definition from the claim
CAS is a division of the American Chemical Society.
53
Copyright 2011 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
Let’s create a synthesis plan for the compound in our set
that has the most literature references
CAS is a division of the American Chemical Society.
54
Copyright 2011 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
October 25, 2013
Almost 2 million reactions have experimental procedure
text directly available for a detailed view on the synthesis
CAS is a division of the American Chemical Society.
55
Copyright 2011 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
Sort, display and analyze options help make sense of
larger reaction answer sets
CAS is a division of the American Chemical Society.
56
Copyright 2011 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
October 25, 2013
Relevant reactions can be moved to SciPlanner
CAS is a division of the American Chemical Society.
57
Copyright 2011 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
October 25, 2013
Two alternative pathways to our compound were
constructed out of reactions from three publications
CAS is a division of the American Chemical Society.
58
Copyright 2011 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
Example: Check novelty and design your synthesis
What did we learn?
•
There are 99 compounds already
disclosed in 31 journal and patent
references
–
J&J seems to dominate the patent
landscape
•
There are at least 24 additional
patents that may influence our
freedom-to-operate
•
Compounds are used in oncology
as well as in neurological diseases
•
Two reaction pathways were
constructed for the most
frequently mentioned substance
CAS is a division of the American Chemical Society.
59
Copyright 2011 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
6.- Más información
Para cualquier duda: mplana@cas.org
help@cas.org
Estrategias de búsqueda
Soporte técnico
Propuestas, ideas,
comentarios
Páginas web de interés:
http://www.cas.org
https://my.cas.org
CAS is a division of the American Chemical Society.
60
Copyright 2011 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
¿Dudas?
CAS is a division of the American Chemical Society.
¿Ideas?
61
¿Comentarios?
Copyright 2011 American Chemical Society. All rights reserved.
This image cannot currently be
display ed.
¡Muchísimas gracias por vuestra atención!
CAS is a division of the American Chemical Society.
62
Copyright 2011 American Chemical Society. All rights reserved.
Míriam Plana
CAS Regional Marketing Manager, Spain & Portugal
mplana@cas.org