La próxima generación de anti-venenos contra la picadura de alacrán

Anuncio
&,(1&,$_ /XQHVGH0DU]RGH_/$81,Ð1'(025(/26_
$&$'(0,$'(&,(1&,$6'(025(/26$&
¢&RPHQWDULRV\VXJHUHQFLDV"¢3UHJXQWDV
VREUHWHPDVFLHQWtÀFRV"&217É&7$126
HGDFPRU#LEWXQDPP[
/D&LHQFLDGHVGH0RUHORVSDUDHOPXQGR
7RGRVORVDUWtFXORVSXEOLFDGRVHQHVWDVHFFLyQGH/D8QLyQGH0RUHORVKDQVLGRUHYLVDGRV\DSUREDGRVSRUHOFRPLWpHGLWRULDOGHOD$FDGHPLDGH&LHQFLDVGH0RUHORV
$&FX\RVLQWHJUDQWHVVRQ'U(QULTXH*DOLQGR)HQWDQHV&RRUGLQDGRU'U(GPXQGR&DOYD'U+HUQiQ/DUUDOGH'U6HUJLR&XHYDV\'U*DEULHO,WXUULDJD
/DSUy[LPDJHQHUDFLyQGHDQWLYHQHQRVFRQWUDODSLFDGXUDGHDODFUiQ
DQWLFXHUSRVSURGXFLGRVHQHOODERUDWRULR
%DOWD]DU%HFHUULO/XMiQ
,QVWLWXWRGH%LRWHFQRORJtD81$0
&DPSXV0RUHORV
0LHPEURGHOD$FDGHPLDGH&LHQ
FLDVGH0RUHORV$&
EDOWD]DU#LEWXQDPP[
DIHFWDQODDFWLYLGDGGHORVFDQDOHV
LyQLFRV FDXVDQGR XQ GHVHTXLOLEULR
TXH WUDH FRPR FRQVHFXHQFLD XQD
VHULH GH VtQWRPDV GH LQWR[LFDFLyQ
ORV FXDOHV SXHGHQ OOHJDU D FDXVDU
ODPXHUWH/DQHXWUDOL]DFLyQGHODV
WR[LQDV GHEH RFXUULU HQ HO PHQRU
/RVYHQHQRVGHDODFUDQHVVRQXQD WLHPSRSRVLEOHSDUDHYLWDUODPXHU
PH]FOD FRPSOHMD GH VXVWDQFLDV WHGHOSDFLHQWHLQWR[LFDGR
PXFKDV GH ODV FXDOHV QR VRQ Wy[L
FDV D ORV KXPDQRV /RV FRPSR 'HVGHKDFHDSUR[LPDGDPHQWH
QHQWHV Wy[LFRV VRQ SULQFLSDOPHQWH DxRVVHXVDEDQ\DORVDQWLYHQHQRV
SURWHtQDVHVGHFLUPHJDPROpFXODV 35,0(5$ *(1(5$&,Ð1 ORV
FRQVWLWXLGDVSRUXQLGDGHVPHQRUHV FXDOHV VH REWHQtDQ DO LQ\HFWDU H[
OODPDGDV DPLQRiFLGRV /DV SUR WUDFWRV GH YHQHQR HQ FDEDOORV ORV
WHtQDV VH HQFXHQWUDQ HQ WRGRV ORV FXDOHVSURGXFHQDQWLFXHUSRVFRQWUD
RUJDQLVPRV \ VRQ UHVSRQVDEOHV ORV FRPSRQHQWHV GHO YHQHQR (VWD
GHO DGHFXDGR IXQFLRQDPLHQWR GH JHQHUDFLyQ GH DQWLYHQHQRV HVWDED
FDGD FpOXOD /DV SULQFLSDOHV WR[L FRQVWLWXLGDSRUHOVXHURGHODVDQ
QDV FDXVDQWHV GHO HQYHQHQDPLHQ JUH GH ORV FDEDOORV LQPXQL]DGRV
WR WLHQHQ XQ WDPDxR DSUR[LPDGR 8QD YH] VHSDUDGR HO VXHUR GH ODV
WHtQDV GLVWLQWDV D ORV DQWLFXHUSRV HPEDUJRDSHVDUGHLQ\HFWDUDKRUD &(5$ *(1(5$&,Ð1 GH DQWL
,JVLQPXQRJOREXOLQDV
LQPXQRJOREXOLQDVSXUDVODVFRQVH YHQHQRVYLJHQWHHQODDFWXDOLGDG
FXHQFLDVVHJXtDQVLHQGRVLPLODUHVD FRQRFLGDFRPRIDERWHUiSLFRVXQD
$QWHHVWDVLWXDFLyQORVFLHQWtÀFRV ODVGHODSULPHUDJHQHUDFLyQORFXDO PH]FODGH)DEŮ GHFDEDOORYHU
VH YLHURQ REOLJDGRV D PHMRUDU ORV ORVRULOOyDUHDOL]DULQYHVWLJDFLRQHV ÀJXUD HV GHFLU ,JV FDUHQWHV GHO
DQWLYHQHQRV GH SULPHUD JHQHUD TXHOHVD\XGDURQDGHWHUPLQDUFXiO IUDJPHQWR )F GLULJLGRV FRQWUD WR
FLyQ FUHDQGR OD 6(*81'$ *( HUDHOSUREOHPD$VLVHHOLPLQDURQ GRV ORV FRPSRQHQWHV GHO YHQHQR
1(5$&,Ð1 FRQVLGHUDQGR TXH YDULRV VHJPHQWRV GH ORV DQWLFXHU LQFOX\HQGR FRPSRQHQWHV QR Wy[L
VL HO SUREOHPD HUD OD SUHVHQFLD GH SRVGHPRVWUDQGRTXHHO´IUDJPHQ FRV 3DUD ORJUDU OD QHXWUDOL]DFLyQ
JUDQGHVFDQWLGDGGHSURWHtQDVGLV WRFULVWDOL]DEOHµ)FYHUÀJXUDHUD GHODVWR[LQDVHQORVSDFLHQWHVHQ
WLQWDVDORVDQWLFXHUSRVWHQGUtDTXH HOFDXVDQWHGHOSUREOHPD
YHQHQDGRVVHDGPLQLVWUDXQDFDQ
WLGDG FRQVLGHUDEOH GH DQWLYHQHQR
HOLPLQDUVH GHO VXHUR WRGR OR TXH
QR IXHUD LQPXQRJOREXOLQDV 6LQ (VWH HVIXHU]R GLR OXJDU D OD 7(5
&217,1Ó$(1/$3É*
9&(.(06(54(57.6$'151%678,(410.15(567',$06(537(4(24(5(06$410$.56$'1'(14(.15(0.$##.,/2,$'$
$&,10$.'(7?/,&$&(.(%4$'$(0(.7(461'(!(4$&47;'(.
'((0(41$.'()(%4(41'((56($@1
'LIHUHQWHVIRUPDWRVGHDQWLFXHUSRV,JDQWLFXHUSRFRPSOHWR
)DE·SURGXFWRGHODHOLPLQDFLyQGHOIUDJPHQWR)FFRQOD
HQ]LPDSHSVLQDVF)YDQWLFXHUSRGHFDGHQDVHQFLOOD9+
UHJLyQYDULDEOHGHODFDGHQDSHVDGD9/UHJLyQYDULDEOHGHOD
FDGHQDOLJHUD&/UHJLyQFRQVWDQWHGHODFDGHQDOLJHUD&+
UHJLRQHVFRQVWDQWHVGHODFDGHQDSHVDGD
GH DPLQRiFLGRV 'HELGR D VX
UHODWLYDPHQWH SHTXHxD WDOOD VH
GLVWULEX\HQ UiSLGDPHQWH D WUDYpV
GHO WRUUHQWH VDQJXtQHR OOHJDQGR D
VXVPROpFXODVEODQFRORVOODPDGRV
FDQDOHVLyQLFRV(VWRVSRURVPROH
FXODUHVSHUPLWHQHOSDVRGHiWRPRV
FDUJDGRVFRPRHOLyQVRGLR1D
'HODVFDQWLGDGHVySWLPDVGHHVWH
LyQ GHQWUR \ IXHUD GH ODV FpOXODV
GHSHQGHHOEXHQIXQFLRQDPLHQWRGH
ODVPLVPDV/DVWR[LQDVGHOYHQHQR
FpOXODVGHODVDQJUHHUDGHVHFDGR\
DVtDSOLFDGRDORVSDFLHQWHVSUHYLD
YDORUDFLyQ GH VX HIHFWLYLGDG (VWD
JHQHUDFLyQGHDQWLYHQHQRVSURYR
FDED KLSHUVHQVLELOLGDG HQ DOJXQRV
GHORVSDFLHQWHVWUDWDGRVDVXPLHQ
GRTXHHUDGHELGDDODSUHVHQFLDHQ
HOVXHURGHDOWDVFDQWLGDGHVGHSUR
0616$.5(*$0$41024(5($5(0.$5'15&$6(*14?$5'(37(&1056$(.(8(061
(.&7$.4(B0($.15/(-14(5(567',$06(5'(37?/,&$'(.$4(2B%.,&$/(9,&$0$
.&10&7451&105,56((0.$24(5(06$&,A0'(70$5(4,('(
(9=/(0(56(A4,&15
:701(92(4,/(06$.
0(.0,8(..$'(.(*$&,A0'(14(.15(56781,06(*4$'$214.15(567',$06(5
$4?$ $41.,0$ ,*7(41$ $.$/$0&$ '(.(&01.A*,&1 '( 106(44(: 37,(0
*$0A/('$..$'(410&(0'4>5'7$4'1$/215(44(,4$'(.'(
7$76.$37,>0*$0A/('$..$'(41:$4.15$.,0'1 4,%('(.$(5&7(.$'(
>&0,&15$%14$614,56$5'(.$ 37,(06$/%,>01%6781/('$..$'(41
0(.0,8(.2$46,&,2$410$0,(.$4$0'$14$.(5'(.37,(0
1%6781 ',2.1/$ '( 2$46,&,2$&,A0 $4?$ (4(5$ $01 47; '(. 1.(*,1
",..,$/537,(0*$0A/('$..$'(410&(:,(*1/,.,114(66*7,.$4'(.
1.(*,1$4:/170637,(0*$0A/('$..$'(.$6$
15 5(,5 ,06(*4$06(5 '( .$ '(.(*$&,A0 5(
24(2$4$410 ,06(05$/(06( '74$06( 8$4,15
/(5(5 4(&,%,(0'1 (064(0$/,(061 (0 .$
$&7.6$' '( ,(0&,$5 7?/,&$5 ( 0*(0,(4?$
%$-1 .$ 572(48,5,A0 '(. '(.(*$'1 '( .$
.,/2,$'$ '( 7?/,&$ (0 14(.15 '7$4'1 <0*(. $4&?$ $/?4(; : 6(0,(0'1
&1/1(064(0$'14(5$.(40$0'1$57461
!=;37(; $6('4=6,&1 '( .$ $&7.6$' '(
,(0&,$5 7?/,&$5 ( 0*(0,(4?$ : $ .$ ($64,; (&,.,$ 4?$5 (A0 241)(514$ '(.
1.(*,114(.15'(7(40$8$&$
'(/=55(&106A&10(.$21:1.1*?56,&1
&114',0$'1 214 .$ 1'(.(*$'$ ,.,$
$6$.=0(:0$,4(&614$'(.$5&7(.$'(
>&0,&15$%14$614,56$5$5?&1/1'(.$&$'(/,$'(,(0&,$5'(14(.15
:(.105(-1'(,(0&,$:(&01.1*?$'(.56$'114(.15
15$.7/0155(/1564$4105$6,5)(&+15&10.15.1*415$.&$0;$'15.15
&7$.(5 510 70 4(D(-1 '(. 5A.,'1 64$%$-1 37( 5( 4($.,;$ (0 (. =4($ '(
&,(0&,$5 (0 (. 0,8(. /(',1 572(4,14 (0 07(5641 (56$'1 56( 6,21 '(
(8(06152(4/,6('(C0,4.$81&$&,A0'(.152$46,&,2$06(5+$&,$.$5',)(4(0
6(5&$44(4$54(.$&,10$'$5&10.$&,(0&,$'($37?574*,4=0.15(567',$06(5
37((070)76741&(4&$01&10)14/$4=0.15&7$'415'(,08(56,*$&,A0:
64$%$-1$0,8(.572(4,14
$4$'$4&106,07,'$'$(56$$&6,8,'$'5(6,(0(&106(/2.$'14($.,;$4.$
5(*70'$1.,/2,$'$'(37?/,&$2$4$5(&70'$4,$(0-70,1'((56($@1$5?
&1/1 .$ ## 1.,/2,$'$ (56$6$. '( 37?/,&$ $ 0,8(. /(',1 572(4,14 (0
5(26,(/%4('(
$'(.(*$&,A0'(14(.15(,;37,(4'$$'(4(&+$0'4>5'7$4'1$/215(44(,4$$4.15$.,0'1
4,%($4?$(4(5$$0147;,(*1/,.,114(66*7,.$4$4?$$41.,0$,*7(41$$.$/$0&$$0,(.$
4$0'$14$.(5
3DUDDFWLYLGDGHVUHFLHQWHVGHOD$FDGHPLD\DUWtFXORVDQWHULRUHVSXHGHFRQVXOWDUZZZDFPRURUJP[
_/XQHVGH0DU]RGH_ &,(1&,$
9,(1('(/$3É* FRPSOHWRV GHELGR D TXH WLHQH XQD GXFH PX\ UiSLGR OD UiSLGD OOHJDGD FRQXQFRQMXQWRGHDQWLFXHUSRVWLSR DFFLGHQWHVHQ0p[LFR&HQWUXURLGHV
PiV UiSLGD GLVWULEXFLyQ HQ HO RUJD
QLVPR\WDPELpQXQDPD\RUHOLPL
QDFLyQ GH ODV WR[LQDV FDSWXUDGDV
&RPR HO HQYHQHQDPLHQWR VH SUR
OR FXDO LPSOLFD LQWURGXFLU DOWDV
FRQFHQWUDFLRQHVGHDQWLFXHUSRVGH
FDEDOORDOKXPDQR3HQVDQGRHQHO
PHMRUDPLHQWR GH OD WHUDSLD DFWXDO
VHGHFLGLyFUHDUXQQXHYRDQWLYH
QHQRPiVHVSHFtÀFR\VHJXUR(VWH
~OWLPRLUtDGLULJLGRH[FOXVLYDPHQWH
FRQWUDODVWR[LQDVPiVDEXQGDQWHV
\Wy[LFDVGHODVHVSHFLHVPiVSRQ
]RxRVDVGHDODFUDQHVPH[LFDQRV
8Q DQWLFXHUSR FRPSOHWR ,J YHU
ÀJXUD HV XQD PROpFXOD GH WDPD
xR FRQVLGHUDEOH XQLGDGHV
GHSHVRPROHFXODU\GHHVWUXFWXUD
PRGXODUHVGHFLUIRUPDGDSRUGRV
WLSRV GH SURWHtQDV OODPDGDV FDGH
QDSHVDGD\FDGHQDOLJHUDSRUVX
WDPDxR UHODWLYR YHU ÀJXUD $ VX
YH]FDGDFDGHQDHVWiFRQIRUPDGD
SRU DO PHQRV GRV VHJPHQWRV XQD
UHJLyQ YDULDEOH 9+ SDUD UHIHULU
VHDODFDGHQDSHVDGD9/SDUDOD
OLJHUD\XQDUHJLyQFRQVWDQWH/D
LQWHUDFFLyQ GH ODV UHJLRQHV YDULD
EOHVHQWUHVtSHUPLWHODIRUPDFLyQ
GHOVLWLRGHDFRSODPLHQWRDVXPR
OpFXOD EODQFR HO DQWtJHQR TXH HQ
QXHVWURFDVRVRQODVWR[LQDVGHOYH
QHQR%DVDGRHQHVWHFRQRFLPLHQ
WRGHODHVWUXFWXUDPRGXODUGHORV
DQWLFXHUSRV GHFLGLPRV SURGXFLU
HQHOODERUDWRULRVyORHOVHJPHQWR
YDULDEOHGHFDGDFDGHQD9+9/
XQLGRV SRU XQ VHJPHQWR FRQHFWRU
VF)Y YHU ÀJXUD 6H GHQRPLQDQ
DQWLFXHUSRV UHFRPELQDQWHV GH
RULJHQ KXPDQR D ORV DQWLFXHUSRV
IDEULFDGRV HQ HO ODERUDWRULR SRU
WpFQLFDV GH ELRORJtD PROHFXODU D
SDUWLUGHPDWHULDOJHQpWLFRKXPD
QR \ XVDQGR EDFWHULDV FRPR ODV
IiEULFDVPROHFXODUHV(VWDYHUVLyQ
PRGHUQD GH ORV DQWLFXHUSRV HQ
ODFXDOVRODPHQWHHVWiSUHVHQWHOD
SDUWHIXQFLRQDOGHORVDQWLFXHUSRV
GH RULJHQ KXPDQR UHGXFH DO Pt
QLPRODSRVLELOLGDGGHUHDFFLRQHV
DGYHUVDVSRVWHULRUHVDODDGPLQLV
WUDFLyQGHOPLVPR
(OVF)YYHUÀJXUDPDQWLHQHODFD
SDFLGDGGHUHFRQRFLPLHQWRDODQWt
JHQRVLPLODUDODGHXQDQWLFXHUSR
FRPSOHWRSHURHVPiVIiFLOGHPD
QLSXODU(VWHIRUPDWRWHQGUtDYDULDV
YHQWDMDV IUHQWH D ORV DQWLFXHUSRV
3DUDDFWLYLGDGHVUHFLHQWHV
GHOD$FDGHPLD\DUWtFXORV
DQWHULRUHVSXHGHFRQVXOWDU
ZZZDFPRURUJP[
GHHVWHIRUPDWRGHDQWLFXHUSRVDORV
FDQDOHV LyQLFRV HYLWD TXH ODV WR[L
QDVVHSHJXHQHYLWDQGRDVtHOHQYH
QHQDPLHQWR$FWXDOPHQWHFRQWDPRV
VF)YTXHVRQFDSDFHVGHQHXWUDOL]DU
ODVSULQFLSDOHVWR[LQDV\ORVYHQHQRV
GHGRVGHODVHVSHFLHVPiVWy[LFDV
\ TXH FDXVDQ HO PD\RU Q~PHUR GH
QR[LXV &HQWUXURLGHV VXIIXVXV VX
IIXVXV\GHODWHUFHUD&HQWUXURLGHV
OLPSLGXVOLPSLGXVHVWDPRVHQYtDV
GHORJUDUOR
Descargar